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Cancer Studies

The Cancer Network supports a wide range of clinical studies which are helping to progress cancer care in Scotland and beyond, and all Scottish research ongoing within the network is registered with the National Institute of Health Research (NIHR).

The cancer clinical trial portfolio is very dynamic and is frequently changing as studies open and close to recruitment. Across Scotland, there is a wide range of clinical trials happening in different disease sites. Information on trials happening in the UK can be found on the UK Clinical Trials Gateway and the Cancer Research UK website. For specific information on trials happening in Scotland please contact your cancer professional or your local cancer research network.

To highlight the clinical trials happening in Scotland the cancer research network will feature current trials happening during the different cancer awareness months that take place throughout the year.

 

   JUNE: MEN'S HEALTH CANCER AWARENESS MONTH 

June is National Men’s Health Month! This month is all about encouraging all men to take care of their bodies by eating well, exercising, and working to prevent disease. The purpose of Men’s Health Month is to heighten the awareness of preventable health problems and encourage early detection and treatment of diseases, including cancer. 

On the 15th-21st June the world also celebrates Men’s Health Week. This is a time to bring awareness to health issues that affect men disproportionately and focuses on getting men to become aware of problems they may have or could develop, and gain the courage to do something about it.

For more information and how you can get involved, visit the Men's Health Forum

 

Prostate Cancer

Prostate cancer is a type of cancer affecting the prostate gland and only affects men. The prostate is a small gland at the base of the bladder. It is about the size of a walnut but gets bigger as men get older. Symptoms to be aware of are an increased urge to urinate, getting up more frequently in the night to urinate or sometimes difficulty emptying the bladder. It is the most common form of cancer in men and affects over 46,000 men a year.

For more information on prostate cancer please visit the CRUK website and Prostate Cancer UK website

 

Trial Spotlight

PATCH

Prostate cancer needs the hormone testosterone to grow so the aim of treatment is to reduce the hormone levels significantly. This is currently done with hormone injections or tablets and patients may have to take these for many years. There are concerns that taking this for such a long time can cause damage to the heart and also increase the risks of bone thinning.

The PATCH trial is looking at the alternative of using oestrogen patches that stick on the skin (transcutaneous patches) which absorb the hormone in a different way into the body, potentially reducing the long term side effects.

Some men on the trial will be given the hormone injections and some will have oestrogen patches.

The aims of the trial are to:

  • See if the patches help men with prostate cancer to live longer
  • Learn more about the side effects, particularly how the patches may affect the heart 

The study is currently recruiting in hospitals in the Glasgow area.

Further information on this trial can be found here

 

STAMPEDE

This trial is comparing hormone therapy alone with a combination of hormone therapy and one or more other treatments for prostate cancer as doctors believe this may be a better long term option.

Trial participants will be given hormone therapy and another treatment such as radiotherapy, chemotherapy or a new drug.

Initial results show:

  • That men who also took the drug Docetaxel on average lived 10 months longer than those just on the standard treatment
  • The trial is also studying the long term effects of taking these drugs


This study is recruiting patients in hospitals in Ayr, Edinburgh, Forth Valley, Glasgow and Inverness.

For further information on this trial please visit the CRUK website

 

ADD-ASPIRIN

After studying the effects of aspirin as a preventative medicine against heart attacks and strokes, doctors want to find out whether giving patients doses of aspirin could also stop their cancer returning after treatment. The study is open to anyone and patients will be given different doses of aspirin or a placebo.

This study is recruiting in Aberdeen, Dundee, Edinburgh, Glasgow, Inverness and various other hospitals in Scotland.

Further information on this trial can be found here

 

Testicular Cancer

This is cancer that develops in the testicles. It is fairly rare and only around 2,400 men are diagnosed with testicular cancer each year in the UK. About 50% of those diagnosed are men under 35 years old. It is very important to examine the testicles regularly to check for any changes and go to the doctor if you notice any pain, lump or swelling in the testicles. If caught in time it can be effectively treated and deaths are rare.

It probably won’t be cancer - about 1 lump in 25 is cancerous - but it could be the sign of another condition which if not treated may cause you - and your sex life - serious problems in the future

For more information on testicular cancer please visit the CRUK website

 

Trial Spotlight  

UK P3BEP

The aim of the study is to determine if accelerated BEP chemotherapy is superior to standard BEP as a 1st line therapy for patients with intermediate and poor-risk metastatic germ cell tumours. Germ cell tumours (GCTs) account for 98% of all testicular cancers.

This study is currently recruiting patients in Glasgow and will be open in Edinburgh and Aberdeen soon.

Further information on this trial can be found here

 

  

CERVICAL SCREENING AWARENESS WEEK

15-21 June 2020

 

                             

Around 3,200 women are diagnosed with cervical cancer in the UK each year.  More than half of cases in the UK are diagnosed in women aged 45 or under. Cervical screening is the most effective way of preventing cervical cancer across the UK.

Coronavirus has changed lots of things. Cervical Screening Awareness Week isn’t one of them! 

If you are due cervical screening or have had a test cancelled, you might be wondering what is going on. Whether it’s your first or your last test, we’re going to help you understand changes to cervical screening as a result of coronavirus, including what to expect if you go.

Further information on cervical cancer and screening can be found here

 

Trial Spotlight

COMICE

This is a Phase II clinical trial of Cediranib and Olaparib maintenance in advanced recurrent Cervical Cancer. This is for patients who have already had chemotherapy treatment which has led to a complete or partial response to the disease or has stabilised the cancer. The trial will also assess levels of toxicity and tolerability to the drug combinations.

COMICE is currently recruiting in Aberdeen, Edinburgh and Glasgow

For more information on this trial please visit the CRUK website