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Cancer Studies

The Cancer Network supports a wide range of clinical studies which are helping to progress cancer care in Scotland and beyond and all Scottish research ongoing within the network is registered with the National Institute of Health Research (NIHR). The cancer clinical trial portfolio is very dynamic and is frequently changing as studies open and close to recruitment. Across Scotland, there is a wide range of clinical trials happening in different disease sites. Information on trials happening in the UK can be found on the UK Clinical Trials Gateway and the Cancer Research UK website. For specific information on trials happening in Scotland please contact your cancer professional or your local cancer research network.

To highlight the clinical trials happening in Scotland the cancer research network will feature current trials happening during the different cancer awareness months that take place throughout the year.

 

July: Cancer Awareness Month – Sarcoma

 

Sarcoma is a rare type of cancer that can either develop in the bones (bone cancer) or in the soft tissues of the body (soft tissue sarcoma). The soft tissues include the muscles, nerves, tendons, ligaments and joints of the body. There are also sarcomas that grow in the gastrointestinal tract, the long tube running from the oesophagus all the way to the back passage known as Gastrointestinal Stromal Tumours (GISTs), some that grow in the female reproductive system (Gynaecological sarcomas) and also some that develop in the areas of the stomach and digestive system (Retroperitoneal sarcomas) 


For further information on all types of Sarcomas please visit the Cancer Research UK website here and additional information can also be found by visiting Sarcoma.org.uk

 

Trial Spotlight

rEECur

This trial is looking at 4 different types of chemotherapy to treat Ewing’s sarcoma that didn’t respond to initial treatment or has come back afterwards. The aim of the trial is to find out which treatment works best and what has the least side effects. More information on the trial can be found here.


This study is recruiting in the Royal Aberdeen Children’s Hospital, Edinburgh and Glasgow.

Further information on rEECur can be found here.

 

EORTC-1202

Liposarcoma is a type of soft tissue sarcoma. Doctors often treat liposarcoma with chemotherapy. However they are uncertain about the best drug to use.

In this trial, researchers are looking at a chemotherapy drug called cabazitaxel (also called Jevtana). The aim of the trial is to see if cabazitaxel can stop advanced liposarcoma from getting worse for those with advanced liposarcoma that has spread or cannot be treated with surgery. This trial is still recruiting in Edinburgh Royal Infirmary.

For further information on this trial please click here.

 

SSG XXII

A trial for patients taking Imatinib for 3 or 5 years for Gastrointestinal Stromal Tumours (GIST). The most common treatment for patients with this type of rare tumour is to have surgery and then targeted (biological) therapy for 3 years. A type of biological therapy often used is Imatinib (Glivec). It works by blocking a protein called tyrosine kinase that tells cells to divide and grow. Blocking this protein might stop cancer cells from coming back. This study will investigate if it is better to take Imatinib for 5 years instead of 3 as per the usual standard treatment and what are the side effects of doing so.

This study is currently recruiting in Glasgow.

For further information please visit here.

 

HGUtS

This study is aimed at women who have been diagnosed with sarcoma of the womb (soft tissues of the womb) which has spread or that can’t be treated with surgery. Usually chemotherapy would be recommended as treatment. Doctors are looking at a drug called cabozantinib, a biological therapy drug, which acts as a cancer growth blocker. It stops signals that cancer cells use to divide and grow. Patients will have chemotherapy followed by either the study drug or a placebo to see if this prevents recurrence of the cancer. They will also study the side effects of using cabozantinib.

The study is recruiting in Glasgow.

Further information can be obtained here.