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The latest publications from NRS Pain and across the pain research community
The World Health Organization's (WHO’s) International Classification of Diseases (ICD) currently has no diagnostic codes for chronic pain. To rectify this, the WHO and the International Association for the Study of Pain (IASP) have developed, for the first time, a series of relevant codes for the forthcoming 11th edition (ICD-11). Blair H. Smith contributed to the WHO/IASP Task Force, and to a series of papers presenting the new ICD-11 chronic pain codes, including an overview and a detailed description of the Neuropathic Pain coding. In particular, with other members of NRS Pain, he led the paper describing their relevance for primary care.
- The IASP classification of chronic pain for ICD-11: applicability in primary care
- The IASP classification of chronic pain for ICD-11: chronic neuropathic pain
- Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11).
Meng W, Adams MJ, Reel P, Rajendrakumar A, Huang Y, Deary IJ, Palmer CNA, McIntosh AM, Smith BH. Genetic correlations between pain phenotypes and depression and neuroticism. European Journal of Human Genetics 2020.
Meng W, Adams MJ, Palmer CNA, 23andMe Research Team, Shi J, Auton A, Ryan KA, Jordan JM, Mitchell BD, Jackson RD, Yau MS, McIntosh AM, Smith BH. Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank. Communications Biology 2019 2 321. Doi 10.1038/s42003-019-0568-2.
Higgins C, Smith BH, Matthews K. Comparison of psychiatric comorbidity in treatment‐seeking, opioid‐dependent patients with versus without chronic pain. Addiction 2019.
Meng W, Chan BW, Harris C, Freidin MB, Hebert HL, Adams MJ, Campbell A, Hayward C, Zheng H, Zhang X, Colvin La, Hales TG, Palmer CAN, Williams FMK, McIntosh A, Smith BH. A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank. Human Molecular Genetics 2020 29 1396 – 1404 ddaa058.
A state-of-the-art review of known risk factors (genetic and non-genetic) for neuropathic pain, published in the Biennial Review of the International Association for the Study Pain. It is to accompany Blair H. Smith’s forthcoming Plenary Lecture at the World Pain Congress, 2021.
- Rates and Trends of gabapentinoid prescribing, co-prescribing of opioids and benzodiazepines, and associated deaths in Scotland
- Data and Measurement for Chronic Pain Services: a project to inform national pain service improvement, current report. This project was established to address the lack of standardised measurement of chronic pain in Scotland, and of services provided to manage chronic pain. This is an important issue as there is no clear way of measuring the prevalence of chronic pain nationally, understanding the demographics and needs of the patient group, the impact chronic pain has on them, or the effectiveness of any service provision or service improvement initiatives which often presents a problem when funding services and treatments for patients.
- SIGN 136 Update, including evidence and recommendations on opioid prescribing, published August 2019
- Fallon, Marie, Jane Walker, Lesley Colvin, Aryelly Rodriguez, Gordon Murray, Michael Sharpe, and Edinburgh Pain Assessment and Management Tool Study Group. "Pain Management in Cancer Center Inpatients: A Cluster Randomized Trial to Evaluate a Systematic Integrated Approach-The Edinburgh Pain Assessment and Management Tool" Journal of Clinical Oncology 36, no. 13 (2018): 1284-1290.
- The Management of Chronic Pain in Children and Young People: A National Clinical Guideline: The main guideline summarises available evidence, combined with consensus group agreement on key recommendations and suggested patient pathways. We have followed the methodology of SIGN 136 and hope that this guideline will facilitate the transition to adult services. Our aim is that this will ensure all health professionals are delivering a consistent, evidence-based approach. Research gaps have not been specifically listed, as these are clear from the key recommendations and current level of evidence associated with these.
Evidence for pain management
- SIGN 136; The Management of Chronic Pain was published in December 2013
- NICE Guideline on Neuropathic Pain
- Management of Chronic Pain in Children and Young People: A National Clinical Guideline.