Professor Bruce Guthrie

Primary Care Clinical Research Champion

Professor Bruce Guthrie is currently Professor of General Practice at the University of Edinburgh where he carries out applied research, to translate basic and clinical research into effective and reliable clinical practice. He works clinically as a GP at Mackenzie Medical Centre in Edinburgh.

He was previously a Medical Research Council Health Services Research Fellow at University of Edinburgh, an National Institute for Health Research post-doctoral research fellow at University of Dundee, a 2006/7 Commonwealth Fund Harkness Fellow in Healthcare Policy at University of California San Francisco where he was also a Visiting Professor in 2010, and Professor of Primary Care Medicine at University of Dundee. 

His main research interests are in the quality and safety of healthcare, particularly in primary care and currently focused on prescribing quality and safety, multimorbidity and the organisation of healthcare. He is a mixed methods researcher and collaborates with researchers from a wide range of disciplines and institutions. The methods he uses include quantitative analysis of large, routine datasets; cluster randomised trials with mixed methods; parallel process evaluations; and qualitative analysis of interview and observational data. Professor Guthrie’s recent and current work includes development and evaluation of interventions to improve polypharmacy, examination of the implications of competing mortality risk for single disease risk prediction, and examination of the applicability of trial evidence to clinical populations. 

He is a member of several grant panels (currently Wellcome and MRC), contributes to undergraduate and postgraduate medical teaching, and supervises and examines MSc and PhD students in Edinburgh and other universities. As well as conducting research, he serves or has served on a number of National Health Service advisory bodies, including the National Institute for Health and Clinical Excellence (NICE) Quality and Outcomes Framework Indicators Advisory Committee and the Scottish Government Polypharmacy Working Group. He was the chair of the guideline development group of the NICE Multimorbidity Clinical Guideline published in late 2016. 

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