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UK Research Paper of the Year - BMJ Awards 2016

UK Research Paper of the Year - BMJ Awards 2016

11th May 2016

The Bronchiolitis Infant Discharge Study (BIDS) published in the Lancet has won the prestigious UK Clinical Paper of the year at the BMJ 2016 Awards.

Bronchiolitis is a common infection in infants and a minority require admission to hospital where oxygen levels are monitored and supplemental oxygen provided to those that fall below an oxygen saturation threshold. The question is where that threshold should lie?

Professor Steve Cunningham of the Department of Child Life and Health, University of Edinburgh and colleagues designed a trial a double-blind trial in which infants (<12 months) were randomised to 90% or 94% oxygen saturation. They looked at outcomes (primary outcome was time to resolution of cough) and the impact on service. Those in the lower oxygen saturation required less time on oxygen supplementation thereby reducing hospital admission times.

BIDS was an exemplary example of networking with 8 hospitals in the UK participating. 615 babies admitted to hospital with bronchiolitis were randomised to the interventional study. Successful recruitment was possible due to the commitment of the study teams involved and the sharing of best practice between study sites. BIDS closed on time and recruited to target. BIDs was HTA funded.

One of the main challenges was recruiting babies during the night when staff resources were tight and parents were anxious. Suitable recruitment strategies were identified and tailored for each Children’s Hospital admissions process. ScotCRN and NIHR- CRN research nurses championed the study, maintaining regular contact with staff, keeping a high profile in the hospital and ensuring that GCP training was rolled out to appropriate staff.

BMJ Judges' commented: "With this study, defining oxygen saturation targets in infants with bronchiolitis can finally move from opinion based to evidence based medicine. The study is elegantly designed and brings robust evidence to treatment decisions concerning one of the most common causes of hospital admission in infants."

The BMJ Awards are the UKs premier medical awards programme recognising and celebrating the inspirational work done by doctors and their teams. The UK Clinical Paper of the Year Award recognises original UK research published in the past year with the greatest potential to significantly improve health and healthcare. 

The paper can be read at:

Full details of all awards and winners can be read at:

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