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Gastroenterology

Gastroenterology

Our role is to support the delivery of high quality clinical research in Gastroenterology and manage participant recruitment to time and target, both for Gastroenterology studies which are led from Scotland, and studies led from other nations which Scottish sites are participating in.  We provide support in the following areas:

  • Managing the study portfolio record
  • Monitoring the attainment of recruitment targets
  • Providing advice on study design and feasibility
  • Troubleshooting issues with poor recruitment
  • Identifying potential sites for studies
  • Facilitating access to resource to support research, for example through Clinical Research Facility (CRF) Research Nurses.

The speciality group has focussed on research into the common chronic inflammatory bowel diseases, Crohn's disease and ulcerative colitis, now affecting up to 1% of the population in Europe.

Gastroenterology Studies

Studies supported by the Gastroenterology Specialty focus on aetiology, pathogenesis, epidemiology, biomarker discovery, and clinical trials of new therapeutic approaches/strategies. Both childhood-onset disease, as well as adult-onset disease are represented on the group's membership team. The following studies are currently led by the UK.

  • TOPPIC -  in prevention of post-operative recurrence after resectional surgery in Crohn's disease
  • ASTIC - stem cell transplantation in Crohn's disease causes and prevention of birth defects
  • IBD-BIOM/CHARACTER - biomarker discovery in inflammatory bowel disease
  • BIOCYCLE -  a randomised trial of withdrawal of biological therapy in Crohn's disease
  • GEM - a study of genetic, environmental, and microbial factors
  • PYRAMID - a study of safety of biologics. 

Patient, carer and public information

NHS Research Scotland is committed to actively involving patients, those who care for them and the public in all aspects of the research process, including shaping future research activity. Read more

Key Contacts

Specialty Lead: Dr Charlie Lees 

Performance Manager: Janet Gilchrist